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1

Physiological carboxy-truncation of α-synuclein potentiates the prion-like formation of pathological inclusions

Sorrentino, Zachary A., Vijayaraghavan, Niran, Gorion, Kimberly-Marie, Riffe, Cara J., Strang, Kevin H, Caldwell, Jason, Giasson, Benoit I.

Journal:

Journal of Biological Chemistry

Year:

2018

Language:

english

File:

PDF, 4.16 MB

english, 2018

2

Distinct differences in prion-like seeding and aggregation between Tau protein variants provide mechanistic insights into tauopathies.

Strang, Kevin H., Croft, Cara L., Sorrentino, Zachary A., Chakrabarty, Paramita, Golde, Todd E., Giasson, Benoit I.

Journal:

Journal of Biological Chemistry

Year:

2018

Language:

english

File:

PDF, 196 KB

english, 2018

3

Phosphorylation of Serine 305 in Tau Inhibits Aggregation

Strang, Kevin H., Sorrentino, Zachary A., Riffe, Cara J., Gorion, Kimberly-Marie M., Vijayaraghavan, Niran, Golde, Todd E., Giasson, Benoit I.

Journal:

Neuroscience Letters

Year:

2018

Language:

english

File:

PDF, 487 KB

english, 2018

4

α-Synuclein and astrocytes: tracing the pathways from homeostasis to neurodegeneration in Lewy body disease

Sorrentino, Zachary A., Giasson, Benoit I., Chakrabarty, Paramita

Journal:

Acta Neuropathologica

Year:

2019

Language:

english

File:

PDF, 2.19 MB

english, 2019

5

Exploring the Peripheral Initiation of Parkinson’s Disease in Animal Models

Sorrentino, Zachary A., Giasson, Benoit I.

Journal:

Year:

2019

Language:

english

File:

PDF, 816 KB

english, 2019

6

Impaired tau-microtubule interactions are prevalent among pathogenic tau variants arising from missense mutations

Xia, Yuxing, Sorrentino, Zachary A., Kim, Justin D., Strang, Kevin H., Riffe, Cara J., Giasson, Benoit I.

Journal:

Journal of Biological Chemistry

Year:

2019

Language:

english

File:

PDF, 10.97 MB

english, 2019

7

Impaired tau-microtubule interactions are prevalent among pathogenic tau variants arising from missense mutations

Xia, Yuxing, Sorrentino, Zachary A., Kim, Justin D., Strang, Kevin H., Riffe, Cara J., Giasson, Benoit I.

Journal:

Journal of Biological Chemistry

Year:

2019

File:

PDF, 10.97 MB

2019

8

Chirped area coupled resonator optical waveguide gyroscope

Toland, John R. E., Kaston, Zachary A., Sorrentino, Christopher, Search, Christopher P.

Journal:

Year:

2011

Language:

english

File:

PDF, 317 KB

english, 2011

9

Zachary Lazar

Zachary Lazar and Christopher Sorrentino

Journal:

Year:

2008

Language:

english

File:

PDF, 1.41 MB

english, 2008

10

A general method for nucleophilic aromatic substitution of aryl fluorides and chlorides with dimethylamine using hydroxide-assisted decomposition of N,N-dimethylforamide

Garcia, Juana, Sorrentino, Jacob, Diller, Emily J., Chapman, Daniel, Woydziak, Zachary R.

Journal:

Synthetic Communications

Year:

2016

Language:

english

File:

PDF, 525 KB

english, 2016

11

ChemInform Abstract: General Method for Nucleophilic Aromatic Substitution of Aryl Fluorides and Chlorides with Dimethylamine Using Hydroxide-Assisted Decomposition of N,N-Dimethylforamide.

Garcia, Juana, Sorrentino, Jacob, Diller, Emily J., Chapman, Daniel, Woydziak, Zachary R.

Journal:

Year:

2016

File:

PDF, 25 KB

2016

12

Robust CNS pathology in transgenic mice following peripheral injection of α-synuclein fibrils

Ayers, Jacob I., Brooks, Mieu M., Rutherford, Nicola J., Howard, Jasie K., Sorrentino, Zachary A., Riffe, Cara J., Giasson, Benoit I.

Journal:

Journal of Virology

Year:

2016

Language:

english

File:

PDF, 1.46 MB

english, 2016

13

Intrastriatal injection of α-synuclein can lead to widespread synucleinopathy independent of neuroanatomic connectivity

Zachary A. Sorrentino,Mieu M.T. Brooks,Vincent Hudson III…

Journal:

Molecular Neurodegeneration

Year:

2017

Language:

english

File:

PDF, 5.40 MB

english, 2017

14

Glucocerebrosidase haploinsufficiency in A53T α-synuclein mice impacts disease onset and course

Tayebi, Nahid, Parisiadou, Loukia, Berhe, Bahafta, Gonzalez, Ashley N., Serra-Vinardell, Jenny, Tamargo, Raphael J., Maniwang, Emerson, Sorrentino, Zachary, Fujiwara, Hideji, Grey, Richard J., Hassan,

Journal:

Molecular Genetics and Metabolism

Year:

2017

Language:

english

File:

PDF, 1.84 MB

english, 2017

15

Distinct differences in prion-like seeding and aggregation between tau protein variants provide mechanistic insights into tauopathies

Strang, Kevin H., Croft, Cara L., Sorrentino, Zachary A., Chakrabarty, Paramita, Golde, Todd E., Giasson, Benoit I.

Journal:

Journal of Biological Chemistry

Year:

2017

Language:

english

File:

PDF, 8.04 MB

english, 2017

16

Localized induction of wild-type and mutant alpha-synuclein aggregation reveals propagation along neuroanatomical tracts

Ayers, Jacob I., Riffe, Cara J., Sorrentino, Zachary A., Diamond, Jeffrey, Fagerli, Eric, Brooks, Mieu, Galaleldeen, Ahmad, Hart, P. John, Giasson, Benoit I.

Journal:

Journal of Virology

Year:

2018

Language:

english

File:

PDF, 1.58 MB

english, 2018

17

Motor neuron loss and neuroinflammation in a model of α-synuclein-induced neurodegeneration

Sorrentino, Zachary A., Xia, Yuxing, Funk, Cory, Riffe, Cara J., Rutherford, Nicola J., Diaz, Carolina Ceballos, Sacino, Amanda N., Price, Nathan D., Golde, Todd E., Giasson, Benoit I., Chakrabarty, P

Journal:

Neurobiology of Disease

Year:

2018

Language:

english

File:

PDF, 21.74 MB

english, 2018

18

Endogenous oligodendroglial alpha-synuclein and TPPP/p25α orchestrate alpha-synuclein pathology in experimental multiple system atrophy models

Mavroeidi, Panagiota, Arvanitaki, Fedra, Karakitsou, Anastasia-Kiriaki, Vetsi, Maria, Kloukina, Ismini, Zweckstetter, Markus, Giller, Karin, Becker, Stefan, Sorrentino, Zachary A., Giasson, Benoit I.,

Journal:

Acta Neuropathologica

Year:

2019

Language:

english

File:

PDF, 19.72 MB

english, 2019

19

Endogenous oligodendroglial alpha-synuclein and TPPP/p25α orchestrate alpha-synuclein pathology in experimental multiple system atrophy models

Mavroeidi, Panagiota, Arvanitaki, Fedra, Karakitsou, Anastasia-Kiriaki, Vetsi, Maria, Kloukina, Ismini, Zweckstetter, Markus, Giller, Karin, Becker, Stefan, Sorrentino, Zachary A., Giasson, Benoit I.,

Journal:

Acta Neuropathologica

Year:

2019

File:

PDF, 19.72 MB

2019

20

Unique α-synuclein pathology within the amygdala in Lewy body dementia: implications for disease initiation and progression

Sorrentino, Zachary A., Goodwin, Marshall S., Riffe, Cara J., Dhillon, Jess-Karan S., Xia, Yuxing, Gorion, Kimberly-Marie, Vijayaraghavan, Niran, McFarland, Karen N., Golbe, Lawrence I., Yachnis, Anth

Journal:

Acta Neuropathologica Communications

Year:

2019

Language:

english

File:

PDF, 25.97 MB

english, 2019

21

Correction to: Endogenous oligodendroglial alpha-synuclein and TPPP/p25α orchestrate alpha-synuclein pathology in experimental multiple system atrophy models

Mavroeidi, Panagiota, Arvanitaki, Fedra, Karakitsou, Anastasia-Kiriaki, Vetsi, Maria, Kloukina, Ismini, Zweckstetter, Markus, Giller, Karin, Becker, Stefan, Sorrentino, Zachary A., Giasson, Benoit I.,

Journal:

Acta Neuropathologica

Year:

2019

Language:

english

File:

PDF, 352 KB

english, 2019

22

The New Global Limb Anatomic Staging System (GLASS) for CLTI: Assessment of its Utility in Two Limb Preservation Centers

Wijnand, Joep, Zarkowsky, Devin, Sorrentino, Thomas, Wu, Bian, Pallister, Zachary, Chung, Jayer, Jan de Borst, Gert, Mills, Joseph, Conte, Michael

Journal:

European Journal of Vascular and Endovascular Surgery

Year:

2019

File:

PDF, 58 KB

2019

23

Carboxy‐terminal truncations of mouse alpha‐synuclein alter aggregation and prion‐like seeding

Sorrentino, Zachary A., Xia, Yuxing, Gorion, Kimberly‐Marie, Hass, Ethan, Giasson, Benoit I.

Journal:

Year:

2020

Language:

english

File:

PDF, 17.94 MB

english, 2020

24

Generation and Characterization of Novel Monoclonal Antibodies TargetingÂ p62/sequestosome-1 Across Human Neurodegenerative Diseases

Trejo-Lopez, Jorge A, Sorrentino, Zachary A, Riffe, Cara J, Prokop, Stefan, Dickson, Dennis W, Yachnis, Anthony T, Giasson, Benoit I

Journal:

Journal of Neuropathology and Experimental Neurology

Year:

2020

Language:

english

File:

PDF, 1.43 MB

english, 2020

25

O4-01-05: COMPARATIVE PRIONOID AND STRAIN PROPERTIES OF TAU AND SYNUCLEIN

Williams, Tosha, Machula, Timothy A., Sorrentino, Zachary, Giasson, Benoit I., Chakrabarty, Paramita

Journal:

Alzheimer's & Dementia

Year:

2019

File:

PDF, 389 KB

2019

26

Carboxy-terminal truncation and phosphorylation of Î±-synuclein elongates survival in a prion-like seeding mouse model of synucleinopathy

Sorrentino, Zachary A., Hass, Ethan, Vijayaraghavan, Niran, Gorion, Kimberly-Marie, Riffe, Cara J., Dhillon, Jess-Karan S., Giasson, Benoit I.

Journal:

Neuroscience Letters

Year:

2020

File:

PDF, 4.57 MB

2020

27

Tau Ser208 phosphorylation promotes aggregation and reveals neuropathologic diversity in Alzheimerâs disease and other tauopathies

Xia, Yuxing, Prokop, Stefan, Gorion, Kimberly-Marie M., Kim, Justin D., Sorrentino, Zachary A., Bell, Brach M., Manaois, Alyssa N., Chakrabarty, Paramita, Davies, Peter, Giasson, Benoit I.

Journal:

Acta Neuropathologica Communications

Year:

2020

File:

PDF, 8.56 MB

2020

28

Novel monoclonal antibodies targeting the RRM2 domain of human TDP-43 protein

Trejo-Lopez, Jorge A., Sorrentino, Zachary A., Riffe, Cara J., Lloyd, Grace M., Labuzan, Sydney A., Dickson, Dennis W., Yachnis, Anthony T., Prokop, Stefan, Giasson, Benoit I.

Journal:

Neuroscience Letters

Year:

2020

File:

PDF, 6.29 MB

2020

29

Differential cross-seeding properties of tau and Î±-synuclein in mouse models of tauopathy and synucleinopathy

Williams, Tosha, Sorrentino, Zachary, Weinrich, Mary, Giasson, Benoit I, Chakrabarty, Paramita

Journal:

Brain Communications

Year:

2020

File:

PDF, 1.58 MB

2020

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